Abstract: Objective To investigate the efficacy of poly (L-lactic acid) application in the rejuvenation of hands, and to analyze the safety of its application. Methods two subjects with aging problems of the hands were given subcutaneous injections of poly-L-lactic acid for hand filling improvement treatment, a detailed protocol of improving treatment was developed and treated, the status of hand improvement in subjects was followed up after treatment, and standardized hand photographs were taken as a contrast basis. Results after 2 month of young onset hand repair surgery on the two propositi, the veins and prominence of the bones of the hand improved significantly in the two propositi, the darker skin complexion state improved, and the collagen content of the hand improved, with gradual fullness of the fingers in subject 1. Three months after the young onset repair surgery, the skin quality of the hand improved significantly more finely in subject 2, and the darker skin complexion problem had largely disappeared, with the bones remaining intact in the two propositi, The venous prominence problems had largely disappeared, the collagen content of the hands had improved significantly, the finger morphology of patient 1 and the problems of dark finger joints had all improved significantly, and none of the 2 subjects had related complications, and the 2 subjects had high satisfaction with the young treatment of polylactic acid hand. Conclusions the use of poly-L-lactic acid in revision treatment of hand rejuvenation has shown remarkable results and a good safety profile. Keywords: Poly-L-Lactic Acid; Younger Age of Hands; Dermal Filling; Safety Preface; Löviselle
聚左旋乳酸在不同类型反复填充后的中面部修复紧致效果 陈丽勇 (厦门思明海峡医疗美容门诊部微整科,福建 厦门 361005) [关键词] 聚左旋乳酸;改善皮肤松弛;修复过度填充;紧致 [中图分类号] R622 [文献标识码] B [文章编号] 1004-4949(2024)02-0052-04
乳酸是葡萄糖或糖原经过糖酵解无氧代谢过程的最终产物。长期以来,乳酸被广泛认为是导致运动能力下降和运动疲劳的代谢废物。然而,近年研究发现,乳酸在机体中具有重要作用:1)乳酸作为能量底物和糖异生前体,不是导致代谢性酸中毒的原因,反而起到缓冲作用;2)乳酸穿梭作用于靶向部位,发挥细胞间信号传导的信使作用;3)乳酸既是脑的重要能源物质,又可以介导运动改善认知和记忆的过程。
聚乳酸材料凭借其独特的优势在美容医学中已得到了越来越广泛的应用,然而其不同异构体由于其体内代谢产物不同,在疗效和安全性方面也不同。因此,本文对聚左旋乳酸和右旋乳酸材料的区别以及其在临床中的应用做一综述,以期为科研和临床工作中不同的需求提供参考依据。