Objective To investigate the efficacy of poly (L-lactic acid) application in the rejuvenation of hands, and to analyzethe safety of its application. Methods two subjects with aging problems of the hands were given subcutaneous injections of poly-L-lactic
眶周色素沉着（periorbital hyperpigmentation，POH）俗称黑眼圈，是临床上常见的一种面部美容问题，主要表现为两侧眼周区域圆形或半圆形的深色外观，呈棕色、深棕色或青紫色，边界不清[1]。因其让人产生一种“衰老”“疲惫”的观感，困扰着许多爱美女性。虽然市场上关于眼周美白的美容产品众多，多种光电技术也用于治疗黑眼圈，但治疗效果偏差较大，并没有完全解决临床需求。